ABSTRACT How the architecture of DNA binding sites dictates the extent of repression of promoters is not well understood.Here, we addressed the importance of the number and information content of the three direct repeats (DRs) in the binding and repression of the icdA promoter by the phosphorylated form of the global Escherichia coli repressor ArcA
In Russian historiography, for more than a century, there have been disputes about the possible reasons for the origin of East Slavic / Old Russian cities.Today, several hypotheses coexist: 1) cities are products of state power, 2) their emergence was influenced THERMAL PRINTERS by the trade and craft factor, 3) the needs of defense influenced the
Genetic diversity helps to survive forest trees in several environmental changes and disease conditions.Different forest management activities such as harvesting, thinning, natural or artificial regeneration, seedlings or coppice forests, fragmentation, and overexploitation have a tremendous influence on the genetic diversity and population structu
High-altitude illnesses, encompassing a spectrum of health threats including Acute Mountain Sickness (AMS), pose significant challenges to individuals exposed to high altitude environments, necessitating effective prophylaxis and immediate management.Given the variability in individual responses to these conditions, accurate prediction of high-alti